Hewlett Packard Enterprise (HPE) has expanded its ProLiant Gen12 server portfolio, introducing new hardware and software capabilities aimed at improving virtualization, edge computing, and operational efficiency. The expansion includes two new server models powered by 5th Gen AMD EPYC processors, enhanced automation features in HPE Compute Ops Management, and broader support for the HPE Morpheus VM Essentials virtualization platform.
The additions to the Gen12 lineup reflect HPE’s strategy to address the growing complexity and performance demands of enterprise workloads. With a focus on scalability, security, and power efficiency, the new offerings are designed to help organizations modernize infrastructure across data centers and edge locations.
The newly introduced HPE ProLiant DL325 and DL345 Gen12 servers support up to 6TB of RAM – double the memory capacity of their predecessors – making them well-suited for memory-intensive applications like virtualization and edge analytics. These systems are built with HPE’s latest security framework, including the next-generation Integrated Lights-Out (iLO 7) management engine, which offers hardware-level protection extending from manufacturing to end-of-life. According to HPE, the system also includes future-ready defenses against quantum computing threats.
To complement the hardware upgrades, HPE is introducing new automation and AI-powered features in HPE Compute Ops Management, a secure, cloud-based server monitoring platform. These tools aim to reduce operational complexity and downtime by enabling centralized visibility, faster root cause analysis, and process approval safeguards. The updates allow IT teams to integrate multi-vendor environments, streamline daily operations, and maintain policy compliance with reduced manual intervention.
HPE claims that early adopters of Compute Ops Management have reported up to a 75% reduction in server management time and nearly five hours less downtime per server annually. Over a three-year period, customers have also seen potential cost savings of up to $152,000 by cutting down on travel and software-related expenses.
Alongside its hardware and management software updates, HPE is promoting HPE Morpheus VM Essentials – a virtualization platform compatible with the ProLiant server line—as a way to reduce costs and improve resource utilization. The open, vendor-neutral software aims to reduce licensing fees by up to 90% while enabling better performance and lower energy use in virtualized environments. When deployed on the new AMD-powered ProLiant servers, HPE says the solution provides both performance gains and operational simplicity.
Azure Local Integrated System
For edge use cases, HPE is also launching the ProLiant DL145 Gen11 server as part of its Azure Local Integrated System. Engineered for edge computing needs in sectors like healthcare, manufacturing, and retail, the compact server is designed for environments with space and power constraints. It supports plug-and-play deployment, secure remote management, and real-time data processing, making it adaptable for distributed systems that require localized computing with cloud integration.
The DL145 comes pre-configured with the latest software and security updates and integrates seamlessly with HPE Compute Ops Management for remote access and monitoring.
According to Krista Satterthwaite, senior vice president and general manager of Compute at HPE, the expanded ProLiant Gen12 portfolio is about aligning with the future needs of enterprise IT. “Enterprise workloads are evolving rapidly, and our Gen12 offerings reflect the need for secure, high-performance, and efficient systems,” she stated. “By combining AMD’s latest processors, enhanced security, and AI-driven management, we’re helping organizations become more agile and resilient.”
The ProLiant DL325 and DL345 Gen12 servers are available for order now and will begin shipping in July. HPE Morpheus VM Essentials software is also available, and the DL145 for Azure Local is currently offered as part of HPE’s edge computing solutions.
With these updates, HPE is reinforcing its position in the highly competitive server and virtualization market, responding to increasing enterprise demand for scalable infrastructure.
